Server
The DIFFUSER server 1.0 is online !
DIFFUSER is a distributed framework to efficiently and comprehensively generate a broad spectrum of heterogeneous features derived from biological sequences, including protein, DNA and RNA sequences. Its computing cluster has 10 nodes, and each of them is equipped with 16 cores and 64 GB memories. When the number of submitted sequences exceeds 200, the submitted sequence will be divided into one subset for every two hundred sequences and distributed to vacant nodes for calculation.
Before using the web server, please note the following tips:
  • The length of submitted sequences should be larger than 9 and less than 5000.
  • The number of each submitted sequences should less than 5000.
  • " * " indicates the parameter is required.
  • " * " indicates submitted sequences should be the same length.
  • " * " indicates the length of sequences should larger than 50 based on PSSM-features.
Enter PROTEIN sequences
Examples help

OR

You can upload a file in fasta format: (example.fasta) help

Please select descriptors you want to generate: help

Simple sequence derived features:






Physicochemical features:
























PSSM Row Transformation Based Descriptors*:




PSSM Column Transformation Based Descriptors*:


PSSM Mixed of Row and Column Transformation Based Descriptors*:




PSSM Combinative Descriptors*:
Predicted Structure composition derived features:


Other profile based features:


Please customize the parameters for Blast: help

Database used for Blast:


Number of iterations used for Blast: Iterations
E-value threshold used for Blast: E-value

Enter DNA sequences
Examples help

OR

You can upload a file in fasta format: (example.fasta) help

Please select descriptors you want to generate: help

Simple sequence derived features:


Physicochemical features:



























Enter RNA sequences
Examples help

OR

You can upload a file in fasta format: (example.fasta) help

Please select descriptors you want to generate: help

Simple sequence derived features:


Physicochemical features:












Predicted Structure composition derived features:




If you find our work useful for your research work, please cite: